Zorbax Eclipse XDB

Zorbax Eclipse Guard Columns from Agilent Technologies

Choosing to use guard columns can help reduce operating expenses, by reducing the frequency of analytical column replacement. The guard column prevents damage caused by particulate matter and strongly adsorbed material. To maintain an adequate capacity for sample impurities, choose a guard column with an internal diameter similar to the column internal diameter.

Ideally, the packing of the guard column should be the same as the analytical column so that the chromatography of the analytical column is not altered. Guard columns contribute to the separation, so you should include a guard column inline during method development. Agilent UHPLC guards provide protection for high-efficiency Poroshell 120 and ZORBAX RRHD and RRHT columns, without reducing performance.

Agilent ZORBAX Eclipse XDB columns – C18, C8, Phenyl and CN – provide four bonded phase choices for method development optimization. These columns provide good peak shape over a wide pH range (2–9) for additional method development flexibility with one family of columns.